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22 / An α-D-mannose ligand equipped with an amine-functionalized linker through a short ethyl spacer
Sialyl Tn (STn) antigen
/ IgA1(222-241)-Tn(232) / N/A
The peptide sequence VGVTETP corresponds to positions 103-109 of the mature IFNα2b protein with α-GalNAc glycosylation (Tn Antigen) ocurring at Thr105
and mechanism of action studies
GP100081: MUC1(126-149)-Tn(131) Pack Size:0.5 mg 22 / An α-D-mannose ligandC103H162N30O37 2412. 57 MUC1 (UniProt ID P15941) synthetic glycopeptide fragment (Pro126 Gly149; UniProt position 126 149, aa length 24) from the variable number tandem repeat (TR) domain. The fragment contains tumour associated carbohydrate antigen (TACA), Tn antigen, O glycosylation ( GalNAc) at Thr131. The C terminus is carboxylic acid. MUC1(126 149) Tn(131) Mucin1; Synthetic MUC 1 (Tn) glycopeptide
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