Along with the classic Oblivion Stone, you have cards like Pernicious Deed and Sarulf, Realm Eater that can deal with multiple permanent types, but take a little while to get going, often over multiple turns
Game Over Game Over is the Teenage Mutant Ninja Turtles Eternal Wrath of God: a black sorcery that destroys all creatures, and it costs less if any player is at or below half their starting life total
As a base starter deck, its a bit lacking in comparison to the Sapphire/Steel deck, but I can see a version of this deck being character heavy so that new Simba never misses his Boost ability trigger
That seemingly sound logic doesnt appear to be applying to the regular Final Fantasy Universes Beyond set either, at least not yet
On the other end of things, original games such as Flesh and Blood have earned respect among hardcore trading card game enthusiasts looking for an alternative to Magic: The Gathering, but dont necessarily have the familiar characters and welcoming gameplay simplicity needed to bring in brand new players to the world of TCGs