binding of isaac four souls gold box exclusive cards The Isaac: Card Game: Ultimate Collection – Asmodee USA box edition of The Binding of Isaac Binding of Isaac Four Souls

Flow of Knowledge and Flow of Ideas both give you tons of cards in your hand, while Engulf the Shore and Floodgate can provide unique board wipe options

Yes, more Commander-focused cards are higher on this list, but that's because of how evergreen they are

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When an opponent's monster declares an attack: You can banish 1 "Nekroz" card from your GY and discard this card

Your deck might hinge on the inclusion of something like Mind Stone , a widely appreciated mana rock that sacs for card draw